HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonyl chloride → HCID 86601887, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | Ammonia methanol dichloromethane | HCID 21584172 | — |
| Reactant | HCID 68816802 | HCID 68816802 | — |
| Product | HCID 86601887 | HCID 86601887 | — |
Reaction Steps
Prepared analogously to Example 1.2.b. from 3-(4-hydroxymethylphenyl)propynoic acid-(4′-chloro-2′-fluorobiphenyl-4-yl)amide and methanesulfonic acid chloride. Yield: 0.23 g (50% of theory); C23H17ClFN2O2S (M=457.91); calc.: molecular ion peak (M+H)+: 456/458; found: molecular ion peak (M+H)+: 456/458; Rf value: 0.5 (silica gel, dichloromethane/methanol/ammonia (20:1:0.1)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-0edd9e6007e6473bb943f6d97e927739 |
| Source note | uspto-grants-2009_09 |