反应详情

Prepared analogously to Example 1.1.d. from 2-[1-(4-iodobenzyl)piperidin-4-yl]propan-2-ol and propynoic acid-(4′-chlorobiphenyl-4-yl)amide. Yield: 45 mg (30% of theory); melting point: 194-195° C.; C30H31ClN2O2 (M=487.04); calc.: molecular ion peak (M+H)+: 487/489; found: molecular ion peak (M+H)+: 487/489; Rf value: 0.3 (silica gel, dichloromethane/methanol/ammonia (10:1:0.1)).

1. customPrepared analogously to Example 1.1.d