HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia methanol dichloromethane → HCID 57845870, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia methanol dichloromethane | HCID 21584172 | — |
| Reactant | HCID 68816491 | HCID 68816491 | — |
| Reactant | Propynoic acid-(4'-chlorobiphenyl-4-yl)amide | HCID 86060771 | — |
| Product | HCID 57845870 | HCID 57845870 | — |
Reaction Steps
Prepared analogously to Example 1.1.d. from 2-[1-(4-iodobenzyl)piperidin-4-yl]propan-2-ol and propynoic acid-(4′-chlorobiphenyl-4-yl)amide. Yield: 45 mg (30% of theory); melting point: 194-195° C.; C30H31ClN2O2 (M=487.04); calc.: molecular ion peak (M+H)+: 487/489; found: molecular ion peak (M+H)+: 487/489; Rf value: 0.3 (silica gel, dichloromethane/methanol/ammonia (10:1:0.1)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-2c609ee9aaa7432e9d1b74ce9370433d |
| Source note | uspto-grants-2009_09 |