HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 1-(4-Iodobenzyl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 4-Iodobenzyl bromide | HCID 954258 | — |
| Solvent | Dichloromethane ethanol | HCID 21584144 | — |
| Product | 1-(4-Iodobenzyl)piperidine | HCID 7537600 | — |
Reaction Steps
Prepared analogously to Example 1.1 c. from 4-iodobenzyl bromide and piperidine. Yield: 0.85 g (67% of theory); C12H16IN (M=301.17); calc.: molecular ion peak (M+H)+: 322; found: molecular ion peak (M+H)+: 302; Rf value: 0.55 (silica gel, dichloromethane/ethanol (20:1)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-ca48e2c9a86d4e9f9c7524ebd61ae45c |
| Source note | uspto-grants-2009_09 |