反应详情

Prepared analogously to Example 1.1.d. from 1-(4-iodobenzyl)piperidine and propynoic acid-(4′-chlorobiphenyl-4-yl)amide. Yield: 6 mg (4% of theory); melting point: 179.5° C.; C27H25ClN2O (M=428.96); calc.: molecular ion peak (H+ H)+: 429/431; found: molecular ion peak (M+H)+: 429/431; Rf value: 0.5 (silica gel, dichloromethane/methanol/ammonia (10:1:0.1)).

1. customPrepared analogously to Example 1.1.d