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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 735028Generated: October 29, 2026

Ffumobqylsjsfv-uhfffaoysa- → 3-[4-(2-Pyrrolidin-1-ylethyl)phenyl]propynoic acid-4-chlorophenylamide

https://huagongshe.com/reaction/735028

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFfumobqylsjsfv-uhfffaoysa-HCID 14491743—
Reactant1-(4-Iodophenethyl)pyrrolidineHCID 68815836—
Product3-[4-(2-Pyrrolidin-1-ylethyl)phenyl]propynoic acid-4-chlorophenylamideHCID 57845706—

Reaction Steps

Prepared analogously to Example 2.1.e. from propynoic acid-(4-chlorophenyl)amide and 1-[2-(4-iodophenyl)ethyl]pyrrolidine. Yield: 80 mg (34.1% of theory); melting point: 153° C.-154° C.; C21H21ClN2O (M=352.86); calc.: molecular ion peak (M+H)+: 353/355; found: molecular ion peak (M+H)+: 353/355.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07592373B2
Source datasetuspto-grants-2009_09
ORD IDord-a4399676efbf44629d1a24b5d07ec496
Source noteuspto-grants-2009_09