HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2,4-dichlorophenyl)prop-2-ynoic acid → 3-(2,4-Dichlorophenyl)propynoic acid-[4-(2-diethylaminopropoxy)phenyl]amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2,4-dichlorophenyl)prop-2-ynoic acid | HCID 228509 | — |
| Reactant | HCID 22609213 | HCID 22609213 | — |
| Reactant | 4-(2-Diethylaminopropoxy)phenylamine | HCID 68816089 | — |
| Product | 3-(2,4-Dichlorophenyl)propynoic acid-[4-(2-diethylaminopropoxy)phenyl]amide | HCID 68816600 | — |
Reaction Steps
Prepared analogously to Example 3.4.c. from 4-(2-diethylaminopropoxy)phenylamine and (2,4-dichlorophenyl)propynoic acid. Yield: 0.41 g (65.2% of theory); melting point: 70° C.-72° C.; C22H24Cl2N2O2 (M=419.35); calc.: molecular ion peak (M+H)+: 419/421/423; found: molecular ion peak (M+H)+: 419/421/423; Rf value: 0.4 (silica gel, dichloromethane/ethanol/ammonia (5:1:0.01)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-faf5335c5c234af2af179a8d830c383f |
| Source note | uspto-grants-2009_09 |