反应详情

Prepared analogously to Example 3.8 from (3-chlorobiphenyl-4-yl)propynoic acid and 4-piperidin-1-ylmethylphenylamine. Yield: 0.35 g (75% of theory); melting point: 260° C.-265° C.; C27H25ClN20*HCl (M=465.41); calc.: molecular ion peak (M+H)+: 429/31 (Cl); found: molecular ion peak (M+H)+: 429/31 (Cl); Rf value: 0.6 (silica gel, dichloromethane/methanol/ammonia (90:10:0.1)).