HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Piperidin-1-ylmethyl)aniline → HCID 68816185, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Piperidin-1-ylmethyl)aniline | HCID 846150 | — |
| Reactant | (2-Chloro-4-trifluoromethylphenyl)propynoic acid | HCID 68817422 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 68816185 | HCID 68816185 | — |
Reaction Steps
Prepared analogously to Example 2.3.f. from 4-piperidin-1-ylmethylphenylamine and (2-chloro-4-trifluoromethylphenyl)propynoic acid. Yield: 170 mg (40% of theory); C22H20ClF3N2O (M=420.86); melting point: 193° C.-195° C.; calc.: molecular ion peak (M−H)−: 419/421(Cl); found: molecular ion peak (M−H)−: 419/421 (Cl); Rf value: 0.5 (silica gel, dichloromethane/methanol (9:1)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-2a29295512b649c9af001cffe55e5e63 |
| Source note | uspto-grants-2009_09 |