HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 62677566, compound → HCID 57845838, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 62677566 | HCID 62677566 | — |
| Reactant | (2-Chloro-4-trifluoromethylphenyl)propynoic acid | HCID 68817422 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 57845838 | HCID 57845838 | — |
Reaction Steps
Prepared analogously to Example 2.3.f. from 4-(2-[1.2.4]triazol-4-ylethoxy)phenylamine and (2-chloro-4-trifluoromethylphenyl)propynoic acid. Yield: 51 mg (39.4% of theory); melting point: 223° C.-227° C.; C20H14ClF3N4O2 (M=434.80); calc.: molecular ion peak (M+H)+: 435/437; found: molecular ion peak (M+H)+: 435/437; Rf value: 0.31 (silica gel, dichloromethane/methanol (9:1)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-53f21d52b2714e43b8143034b527166c |
| Source note | uspto-grants-2009_09 |