Ammonia methanol dichloromethane → HCID 68817646, compound

HRID 735089Notes

Reaction equation

HRID 735089 reaction equation
[Cl:1][C:2]1[CH:16]=[C:15]([N+:17]([O-])=O)[CH:14]=[CH:13][C:3]=1[O:4][CH:5]([CH3:12])[CH2:6][N:7]([CH2:10][CH3:11])[CH2:8][CH3:9].ClCCl.CO.N>CO>[Cl:1][C:2]1[CH:16]=[C:15]([NH2:17])[CH:14]=[CH:13][C:3]=1[O:4][CH:5]([CH3:12])[CH2:6][N:7]([CH2:8][CH3:9])[CH2:10][CH3:11]

Participants

4

Reactant 2

HCID 21584172Ammonia methanol dichloromethaneHCID 68816364HCID 68816364, compound

Product 1

HCID 68817646HCID 68817646, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Prepared analogously to Example 3.1.b. from [2-(2-chloro-4-nitrophenoxy)propyl]diethylamine in methanol in a reaction time of 8 hours. Yield: 6.7 g (93.5% of theory); C13H21ClN2O (M=256.77); calc.: molecular ion peak (M+H)+: 257/259; found: molecular ion peak (M+H)+: 257/259; Rf value: 0.4 (silica gel, dichloromethane/methanol/ammonia (50:10:0.1)).

Workup

  1. customPrepared analogously to Example 3.1.b
  2. customin a reaction time of 8 hours

Sources & evidence

ORD record
ord-2ab00025103345b6bee85ac1388a6aa0
Source dataset
uspto-grants-2009_09
Patent number
US07592373B2

Reaction notes

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