HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Amino-1-(2-pyrrolidin-1-ylethyl)indole → HCID 57845822, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Amino-1-(2-pyrrolidin-1-ylethyl)indole | HCID 11390574 | — |
| Reactant | Ammonia methanol dichloromethane | HCID 21584172 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | 3-(2,4-dichlorophenyl)prop-2-ynoic acid | HCID 228509 | — |
| Product | HCID 57845822 | HCID 57845822 | — |
Reaction Steps
Prepared analogously to Example 3.1.e. from 5-amino-1-(2-pyrrolidin-1-ylethyl)-1H-indole and (2,4-dichlorophenyl)propynoic acid in THF as solvent. Yield: 133 mg (31.2% of theory); C23H21Cl2N3O (M=426.34); melting point: 127° C.-129° C.; calc.: molecular ion peak (M+H)+: 426/428/430; found: molecular ion peak (M+H)+: 426/428/430; Rf value: 0.4 (silica gel, dichloromethane/methanol/ammonia (90:10:1)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-c7e4f14e65e8419dba77c160f29bc7e6 |
| Source note | uspto-grants-2009_09 |