反应详情

Prepared analogously to Example 3.1.e. from 5-amino-1-(2-pyrrolidin-1-ylethyl)-1H-indole and (2,4-dichlorophenyl)propynoic acid in THF as solvent. Yield: 133 mg (31.2% of theory); C23H21Cl2N3O (M=426.34); melting point: 127° C.-129° C.; calc.: molecular ion peak (M+H)+: 426/428/430; found: molecular ion peak (M+H)+: 426/428/430; Rf value: 0.4 (silica gel, dichloromethane/methanol/ammonia (90:10:1)).

1. customPrepared analogously to Example 3.1.e