反应详情

Prepared analogously to Example 3.1.e. from 5-amino-2-(2-pyrrolidin-1-ylethyl)benzoxazole and (2,4-dichlorophenyl)propynoic acid. Yield: 43 mg (33.1% of theory); C22H19Cl2N3O2 (M=428.32); melting point: 130° C.; calc.: molecular ion peak (M+H)+: 428/430/432; found: molecular ion peak (M+H)+: 428/430/432; C13H17N3O (M=231.30); calc.: molecular ion peak (M+H)+: 232; found: molecular ion peak (M+H)+: 232; Rf value: 0.21 (silica gel, dichloromethane/methanol/ammonia (10:1:0.1)).

1. customPrepared analogously to Example 3.1.e