HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia methanol dichloromethane → Ethyl 5-amino-2-[2-(diethylamino)ethoxy]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia methanol dichloromethane | HCID 21584172 | — |
| Reactant | Ethyl 2-(2-diethylaminoethoxy)-5-nitrobenzoate | HCID 57632929 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Ethyl 5-amino-2-[2-(diethylamino)ethoxy]benzoate | HCID 57632512 | — |
Reaction Steps
Prepared analogously to Example 3.1.b. from 0.30 g ethyl 2-(2-diethylaminoethoxy)-5-nitrobenzoate in ethyl acetate. Yield: 0.27 g (100% of theory); C15H24N2O3 (M=280.37); calc.: molecular ion peak (M+H)+: 281; found: molecular ion peak (M+H)+: 281; Rf value: 0.40 (silica gel, dichloromethane/methanol/ammonia (39:1:0.1)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-631e434f480f4e568b68718c39541a1a |
| Source note | uspto-grants-2009_09 |