HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68818181, compound → 3-Chloro-4-[2-(4-methylpiperidin-1-yl)ethoxy]phenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68818181 | HCID 68818181 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | 3-Chloro-4-[2-(4-methylpiperidin-1-yl)ethoxy]phenylamine | HCID 57892112 | — |
Reaction Steps
Prepared analogously to Example 3.1.b. from 1-[2-(2-chloro-4-nitrophenoxy)ethyl]4-methylpiperidine. Yield: 3.66 g (59% of theory); C14H21ClN2O (M=268.78); calc.: molecular ion peak (M+H)+: 269/271; found: molecular ion peak (M+H)+: 269/271; Rf value: 0.52 (silica gel, dichloromethane/methanol (9:1)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-7f09f6da8bf646fd8beb1d10626e8be0 |
| Source note | uspto-grants-2009_09 |