HCID 68817390, compound → HCID 68817651, compound

HRID 735134Notes

Reaction equation

HRID 735134 reaction equation
[CH3:1][O:2][C:3]1[CH:18]=[C:17]([N+:19]([O-])=O)[CH:16]=[CH:15][C:4]=1[O:5][CH2:6][CH2:7][N:8]1[CH2:12][CH2:11][CH2:10][C@H:9]1[CH2:13][OH:14]>ClCCl.CO>[NH2:19][C:17]1[CH:16]=[CH:15][C:4]([O:5][CH2:6][CH2:7][N:8]2[CH2:12][CH2:11][CH2:10][C@H:9]2[CH2:13][OH:14])=[C:3]([O:2][CH3:1])[CH:18]=1

Participants

3

Reactant 1

HCID 68817390HCID 68817390, compound

Product 1

HCID 68817651HCID 68817651, compound

Reagents, catalysts & solvents 1

HCID 21226129Dichloromethane methanolSolvent

Procedure

Prepared analogously to Example 3.1.b. from {(S)-1-[2-(2-methoxy-4-nitrophenoxy)ethyl]pyrrolidin-2-yl}methanol. Yield: 0.15 g (83.4% of theory); C14H22N2O3 (M=266.34); calc.: molecular ion peak (M+H)+: 267; found: molecular ion peak (M+H)+: 267; Rf value: 0.15 (silica gel, dichloromethane/methanol 9:1)).

Workup

  1. customPrepared analogously to Example 3.1.b

Sources & evidence

ORD record
ord-de6479134b0e43f39a1b24253bd637e9
Source dataset
uspto-grants-2009_09
Patent number
US07592373B2

Reaction notes

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