HCID 21101391, compound → HCID 68816035, compound

HRID 735149Notes

Reaction equation

HRID 735149 reaction equation
[CH3:1][O:2][C:3]1[CH:19]=[C:18]([N+:20]([O-])=O)[CH:17]=[CH:16][C:4]=1[O:5][CH2:6][CH2:7][N:8]1[CH:13]([CH3:14])[CH2:12][CH2:11][CH2:10][CH:9]1[CH3:15]>ClCCl.CO>[CH3:15][CH:9]1[CH2:10][CH2:11][CH2:12][CH:13]([CH3:14])[N:8]1[CH2:7][CH2:6][O:5][C:4]1[CH:16]=[CH:17][C:18]([NH2:20])=[CH:19][C:3]=1[O:2][CH3:1]

Participants

3

Reactant 1

HCID 21101391HCID 21101391, compound

Product 1

HCID 68816035HCID 68816035, compound

Reagents, catalysts & solvents 1

HCID 21226129Dichloromethane methanolSolvent

Procedure

Prepared analogously to Example 3.1.b. from 0.84 g (2.72 mmol) of 1-[2-(2-methoxy-4-nitrophenoxy)ethyl]-2,6-dimethylpiperidine. Yield: 0.65 g (86% of theory); C16H26N2O2 (M=278.39); calc.: molecular ion peak (M+H)+: 279; found: molecular ion peak (M+H)+: 279; Rf value: 0.1 (silica gel, dichloromethane/methanol (9:1)).

Workup

  1. customPrepared analogously to Example 3.1.b

Sources & evidence

ORD record
ord-8dfaad4764ed4969af08a4f56a73a636
Source dataset
uspto-grants-2009_09
Patent number
US07592373B2

Reaction notes

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