HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68816510, compound → HCID 57845843, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68816510 | HCID 68816510 | — |
| Reactant | (2-Chloro-4-trifluoromethylphenyl)propynoic acid | HCID 68817422 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 57845843 | HCID 57845843 | — |
Reaction Steps
Prepared analogously to Example 2.3.f. from (2-chloro-4-trifluoromethylphenyl)propynoic acid and 6-amino-2-piperidin-2-ylquinoline. Yield: 170 mg (37.1% of theory); melting point: 176° C.-179° C.; C24H19ClF3N3O (M=457.88); calc.: molecular ion peak (M+H)+: 456/458; found: molecular ion peak (M+H)+: 456/458; Rf value: 0.62 (silica gel, dichloromethane/methanol (19:1)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-85b759305ba24fb88124de2131ae1583 |
| Source note | uspto-grants-2009_09 |