HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 4,4'-Dimethylstilbene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 4-Methylbenzaldehyde | HCID 7725 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Phosphonium, ((4-methylphenyl)methyl)triphenyl-, bromide (1:1) | HCID 11797662 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4,4'-Dimethylstilbene | HCID 137621 | 71% |
Reaction Steps
2.4 g(5.37 mmol) of (4-methylbenzyl)triphenylphosphonium bromide and 0.98 g(60%, 24.4 mmol) of NaH were refluxed in toluene for 6 hours. After cooled down, 0.586 g(4.88 mmol) of 4-methylbenzaldehyde was introduced gradually to the solution to be refluxed again for 6 hours. The resulted product was treated with water to be extracted with ethyl acetate. The solvent was distilled off and the residue was recrystallized in ethanol. Yield; 71%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592475B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-fa0b63b791f04268a0b40ec85769b29e |
| Source note | uspto-grants-2009_09 |