反应详情

2.4 g(5.37 mmol) of (4-methylbenzyl)triphenylphosphonium bromide and 0.98 g(60%, 24.4 mmol) of NaH were refluxed in toluene for 6 hours. After cooled down, 0.586 g(4.88 mmol) of 4-methylbenzaldehyde was introduced gradually to the solution to be refluxed again for 6 hours. The resulted product was treated with water to be extracted with ethyl acetate. The solvent was distilled off and the residue was recrystallized in ethanol. Yield; 71%.

1. temperatureAfter cooled down
2. temperatureto be refluxed again for 6 hours
3. extractionto be extracted with ethyl acetate
4. distillationThe solvent was distilled off
5. customthe residue was recrystallized in ethanol