Lithium hydroxide, monohydrate → HCID 10481552, compound

HRID 735378Notes

Reaction equation

HRID 735378 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[C:12]3[CH:13]=[CH:14][C:15]([Se:23][C:24]#[C:25][C:26]4[CH:35]=[CH:34][C:29]([C:30]([O:32]C)=[O:31])=[CH:28][CH:27]=4)=[CH:16][C:17]=3[C:18]([CH3:22])([CH3:21])[CH2:19][CH:20]=2)=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].O.[OH-].[Li+]>>[C:1]([C:5]1[CH:6]=[CH:7][C:8]([C:11]2[C:12]3[CH:13]=[CH:14][C:15]([Se:23][C:24]#[C:25][C:26]4[CH:35]=[CH:34][C:29]([C:30]([OH:32])=[O:31])=[CH:28][CH:27]=4)=[CH:16][C:17]=3[C:18]([CH3:22])([CH3:21])[CH2:19][CH:20]=2)=[CH:9][CH:10]=1)([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 2

HCID 168937Lithium hydroxide, monohydrateHCID 86601143HCID 86601143, compound

Product 1

HCID 10481552HCID 10481552, compound

Procedure

In a manner similar to that of Example 1 g, by reacting 0.28 g (0.5 mmol) of methyl 4-[5-(4-tert-butylphenyl)-8,8-dimethyl-7,8-dihydro-2-naphthylselanylethynyl]benzoate with 0.28 g (6.6 mmol) of lithium hydroxide monohydrate, a cream-colored powder is obtained (0.08 g; yield=30%; m.p.=231° C.).

Workup

  1. customa cream-colored powder is obtained (0.08 g; yield=30%; m.p.=231° C.)

Sources & evidence

ORD record
ord-4c626d5716c548ce8a9d59377ad6a003
Source dataset
uspto-grants-2009_09
Patent number
US07592478B2

Reaction notes

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