Lithium hydroxide, monohydrate → HCID 10003702, compound

HRID 735392Notes

Reaction equation

HRID 735392 reaction equation
[CH3:1][C:2]1([CH3:35])[C:11]2[CH:10]=[C:9]([C:12]([C:14]3[CH:15]=[C:16]4[C:21](=[CH:22][CH:23]=3)[CH:20]=[C:19]([C:24]([O:26]C)=[O:25])[CH:18]=[CH:17]4)=[O:13])[CH:8]=[CH:7][C:6]=2[C:5]([C:28]2[CH:33]=[CH:32][C:31]([CH3:34])=[CH:30][CH:29]=2)=[CH:4][CH2:3]1.O.[OH-].[Li+]>>[CH3:1][C:2]1([CH3:35])[C:11]2[CH:10]=[C:9]([C:12]([C:14]3[CH:15]=[C:16]4[C:21](=[CH:22][CH:23]=3)[CH:20]=[C:19]([C:24]([OH:26])=[O:25])[CH:18]=[CH:17]4)=[O:13])[CH:8]=[CH:7][C:6]=2[C:5]([C:28]2[CH:29]=[CH:30][C:31]([CH3:34])=[CH:32][CH:33]=2)=[CH:4][CH2:3]1

Participants

3

Reactant 2

HCID 168937Lithium hydroxide, monohydrateHCID 69064315HCID 69064315, compound

Product 1

HCID 10003702HCID 10003702, compoundYield 98%

Procedure

In a manner similar to that of Example 22e, by reacting 0.5 g (1 mmol) of methyl 6-(8,8-dimethyl-5-p-tolyl-7,8-dihydro-2-naphthylcarbonyl)-2-naphthalenecarboxylate (described in Example 22c) with 0.126 g (3 mmol) of lithium hydroxide hydrate, a solid is obtained (0.48 g; yield=98%; m.p.=267° C.).

Workup

  1. customa solid is obtained (0.48 g; yield=98%; m.p.=267° C.)

Sources & evidence

ORD record
ord-7a7f2b9126914139954afde0ebfab28b
Source dataset
uspto-grants-2009_09
Patent number
US07592478B2

Reaction notes

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