HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 11663947, compound → HCID 11627513, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 11663947 | HCID 11663947 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | HCID 11627513 | HCID 11627513 | 55.2% |
Reaction Steps
A solution of 8-{4-[2-(2,4,6-trifluorobenzyl)-7-(trifluoromethyl)-2H-indazol-3-yl]phenyl}-1,4-dioxa-8-azaspiro[4.5]decane (0.195 g, 0.36 mmol) in 2 mL of formic acid was heated at 70° C. for 2 hours. The solvent was evaporated and the residue purified by flash chromatography (CH2Cl2-EtOAc, 19:1) to give 0.1 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592363B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-0cff62c784f14457a65252643c9881bf |
| Source note | uspto-grants-2009_09 |