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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 735445Generated: October 31, 2026

HCID 11663947, compound → HCID 11627513, compound

https://huagongshe.com/reaction/735445

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 11663947HCID 11663947—
SolventFormic AcidHCID 284—
ProductHCID 11627513HCID 1162751355.2%

Reaction Steps

A solution of 8-{4-[2-(2,4,6-trifluorobenzyl)-7-(trifluoromethyl)-2H-indazol-3-yl]phenyl}-1,4-dioxa-8-azaspiro[4.5]decane (0.195 g, 0.36 mmol) in 2 mL of formic acid was heated at 70° C. for 2 hours. The solvent was evaporated and the residue purified by flash chromatography (CH2Cl2-EtOAc, 19:1) to give 0.1 g of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07592363B2
Source datasetuspto-grants-2009_09
ORD IDord-0cff62c784f14457a65252643c9881bf
Source noteuspto-grants-2009_09