HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Bromophenyl)butanoyl chloride → 4-(4-Bromophenyl)-N-(3-cyano-4-(isopropylsulfonyl)phenyl)butanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Bromophenyl)butanoyl chloride | HCID 246776 | — |
| Reactant | 5-Amino-2-(isopropylsulfonyl)benzonitrile | HCID 57448207 | — |
| Reactant | 4-(4-Bromo-2-methylphenyl)-N-(3-cyano-4-(ethylsulfonyl)phenyl)butanamide | HCID 57842660 | — |
| Product | 4-(4-Bromophenyl)-N-(3-cyano-4-(isopropylsulfonyl)phenyl)butanamide | HCID 57842772 | 92% |
Reaction Steps
Using a procedure analogous to that used to prepare 8B, 9B (364 mg, 1.62 mmol) was reacted with 4-(4-bromophenyl)butyric acid chloride to give 9C (667 mg, 92%). MS (ESI) m/z 449.1, 451.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592331B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-7597159c96b94d3c964448fcfaa7b92e |
| Source note | uspto-grants-2009_09 |