HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Bromophenyl)butanoyl chloride → 4-(4-Bromophenyl)-N-(4-(tert-butylsulfonyl)-3-cyanophenyl)butanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Bromophenyl)butanoyl chloride | HCID 246776 | — |
| Reactant | 4-(4-Bromo-2-methylphenyl)-N-(3-cyano-4-(ethylsulfonyl)phenyl)butanamide | HCID 57842660 | — |
| Reactant | 5-Amino-2-(tert-butylsulfonyl)benzonitrile | HCID 57842823 | — |
| Product | 4-(4-Bromophenyl)-N-(4-(tert-butylsulfonyl)-3-cyanophenyl)butanamide | HCID 57842696 | 100% |
Reaction Steps
Using a procedure analogous to that used to prepare 8B, 10B (250 mg, 1.05 mmol) was reacted with 4-(4-bromophenyl)butyric acid chloride to give 10C (493 mg, 100%). MS (ESI) m/z 461.2, 463.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592331B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-b5940844479a4f58bb489dd772a7ed62 |
| Source note | uspto-grants-2009_09 |