HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 57842800, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | (3-Cyanophenyl)carbamic acid 2-[4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-phenyl]ethyl ester | HCID 57842566 | — |
| Reactant | 4-(4-Boronophenyl)butanoic acid | HCID 57842598 | — |
| Product | HCID 57842800 | HCID 57842800 | 48% |
Reaction Steps
Using a procedure analogous to that used to prepare 2B, 11B (434 mg, 1.15 mmol) was reacted with NaOH to give 11C (170 mg, 48%) as a solid. 1H NMR (400 MHz, THF-d8) δ 2.98 (t, J=7.03 Hz, 2 H), 4.38 (t, J=6.81 Hz, 2 H), 7.10 (s, 2 H), 7.22 (d, J=7.91 Hz, 1 H), 7.30 (d, J=7.47 Hz, 1 H), 7.39 (t, J=7.91 Hz, 1 H), 7.68 (d, J=8.35 Hz, 1 H), 7.73 (d, J=8.35 Hz, 2 H), 7.87 (s, 1 H), 9.11 (s, 1 H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592331B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-628d012e0721480bad7452bf39284762 |
| Source note | uspto-grants-2009_09 |