HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → tert-Butyl 5-(4-(4-bromophenyl)butanamido)-2-(ethylsulfonyl)benzyl(methyl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | [3-[(tert-Butoxycarbonyl-methyl-amino)-methyl]-4-(propane-2-sulfonyl)-phenyl]-carbamic acid phenyl ester | HCID 57842905 | — |
| Reactant | tert-Butyl 5-(4-(4-bromophenyl)butanamido)-2-(ethylthio)benzyl(methyl)carbamate | HCID 57956370 | — |
| Product | tert-Butyl 5-(4-(4-bromophenyl)butanamido)-2-(ethylsulfonyl)benzyl(methyl)carbamate | HCID 57842603 | 88% |
Reaction Steps
Using a procedure analogous to that used for preparation of 16G, 17B (0.460 g, 0.88 mmol) was reacted with mCPBA (0.500 g, 2.23 mmol) to give 17C (0.428 g, 88%) as a white foam. MS (ESI) m/z 555.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592331B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-2e1409d974544f1eaa7a107cc12de30e |
| Source note | uspto-grants-2009_09 |