HRID735531

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID70297

Benzenecarboperoxoic acid, 3-chloro-

C7H5ClO3

结构：CC(C)S(=O)(=O)c1ccc(NC(=O)Oc2ccccc2)cc1CN(C)C(=O)OC(C)(C)C

HCID57842905

未命名化合物

结构：CCSc1ccc(NC(=O)CCCc2ccc(Br)cc2)cc1CN(C)C(=O)OC(C)(C)C

HCID57956370

未命名化合物

PRODUCTS

生成物

结构：CCS(=O)(=O)c1ccc(NC(=O)CCCc2ccc(Br)cc2)cc1CN(C)C(=O)OC(C)(C)C

HCID57842603

未命名化合物

收率 88%

PROCEDURE

实验过程

Using a procedure analogous to that used for preparation of 16G, 17B (0.460 g, 0.88 mmol) was reacted with mCPBA (0.500 g, 2.23 mmol) to give 17C (0.428 g, 88%) as a white foam. MS (ESI) m/z 555.0 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2e1409d974544f1eaa7a107cc12de30e
来源数据集: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07592331B2
来源说明: uspto-grants-2009_09

反应 SMILES

C1([O:7][C:8](=O)[NH:9][C:10]2[CH:15]=[CH:14][C:13]([S:16](C(C)C)(=[O:18])=[O:17])=[C:12]([CH2:22][N:23]([C:25]([O:27][C:28]([CH3:31])([CH3:30])[CH3:29])=[O:26])[CH3:24])[CH:11]=2)C=CC=CC=1.[Br:33][C:34]1[CH:39]=[CH:38][C:37]([CH2:40][CH2:41][CH2:42]C(NC2C=CC(SCC)=C(C=2)CN(C)C(=O)OC(C)(C)C)=O)=[CH:36][CH:35]=1.[CH:65]1C=C(Cl)C=C(C(OO)=O)[CH:66]=1>>[Br:33][C:34]1[CH:39]=[CH:38][C:37]([CH2:40][CH2:41][CH2:42][C:8]([NH:9][C:10]2[CH:15]=[CH:14][C:13]([S:16]([CH2:65][CH3:66])(=[O:18])=[O:17])=[C:12]([CH:11]=2)[CH2:22][N:23]([CH3:24])[C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:31])[CH3:30])=[O:7])=[CH:36][CH:35]=1