HRID735535

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID70297

Benzenecarboperoxoic acid, 3-chloro-

C7H5ClO3

结构：CC(C)Sc1ccc(NC(=O)CCCc2ccc(Br)cc2)cc1CN(C)C(=O)OC(C)(C)C

HCID57842807

未命名化合物

结构：CC(C)S(=O)(=O)c1ccc(NC(=O)Oc2ccccc2)cc1CN(C)C(=O)OC(C)(C)C

HCID57842905

未命名化合物

PRODUCTS

生成物

结构：CC(C)S(=O)(=O)c1ccc(NC(=O)CCCc2ccc(Br)cc2)cc1CN(C)C(=O)OC(C)(C)C

HCID57842659

未命名化合物

收率 97%

PROCEDURE

实验过程

Using a procedure analogous to that used for preparation of 16G, 18A (0.642 g, 1.20 mmol) was reacted with mCPBA (0.672 g, 3.00 mmol) to give 18B (0.660 g, 97%) as a white solid. MS (ESI) m/z 568.9 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-38eaf5e21e3244a686420b278dad08a2
来源数据集: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07592331B2
来源说明: uspto-grants-2009_09

反应 SMILES

C1(O[C:8](=[O:32])[NH:9][C:10]2[CH:15]=[CH:14][C:13]([S:16]([CH:19]([CH3:21])[CH3:20])(=[O:18])=[O:17])=[C:12]([CH2:22][N:23]([C:25]([O:27][C:28]([CH3:31])([CH3:30])[CH3:29])=[O:26])[CH3:24])[CH:11]=2)C=CC=CC=1.[Br:33][C:34]1[CH:39]=[CH:38][C:37]([CH2:40][CH2:41][CH2:42]C(NC2C=CC(SC(C)C)=C(C=2)CN(C)C(=O)OC(C)(C)C)=O)=[CH:36][CH:35]=1.C1C=C(Cl)C=C(C(OO)=O)C=1>>[Br:33][C:34]1[CH:39]=[CH:38][C:37]([CH2:40][CH2:41][CH2:42][C:8]([NH:9][C:10]2[CH:15]=[CH:14][C:13]([S:16]([CH:19]([CH3:21])[CH3:20])(=[O:18])=[O:17])=[C:12]([CH:11]=2)[CH2:22][N:23]([CH3:24])[C:25](=[O:26])[O:27][C:28]([CH3:31])([CH3:29])[CH3:30])=[O:32])=[CH:36][CH:35]=1