HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → tert-Butyl 5-(4-(4-bromo-2-ethylphenyl)butanamido)-2-(isopropylsulfonyl)benzyl(methyl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | tert-Butyl 5-(4-(4-bromo-2-ethylphenyl)butanamido)-2-(isopropylthio)benzyl(methyl)carbamate | HCID 57842757 | — |
| Reactant | [3-[(tert-Butoxycarbonyl-methyl-amino)-methyl]-4-(propane-2-sulfonyl)-phenyl]-carbamic acid phenyl ester | HCID 57842905 | — |
| Product | tert-Butyl 5-(4-(4-bromo-2-ethylphenyl)butanamido)-2-(isopropylsulfonyl)benzyl(methyl)carbamate | HCID 57842767 | 69% |
Reaction Steps
Using a procedure analogous to that described for the preparation of 16G, 21B (0.700 g, 1.25 mmol) was reacted with mCPBA (0.695 g, 3.10 mmol) to give 21C (0.513 g, 69%). MS (ESI) m/z 595, 597.4 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592331B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-0b90747e3d69470d87caec24d2d59e1c |
| Source note | uspto-grants-2009_09 |