2-(4-Bromo-2,6-dimethylphenyl)ethanol → HCID 57842545, 화합물

HRID 735589노트

반응식

HRID 735589 반응식
[C:1]([C:3]1[CH:4]=[C:5]([NH:14][C:15](=[O:27])[O:16][CH2:17][CH2:18][C:19]2[CH:24]=[CH:23][C:22]([Br:25])=[CH:21][C:20]=2[CH3:26])[CH:6]=[CH:7][C:8]=1[S:9]([CH2:12][CH3:13])(=[O:11])=[O:10])#[N:2].Br[C:29]1C=C(C)C(CCO)=C(C)C=1.C(C1C=C(NC(=O)OC2C=CC=CC=2)C=CC=1S(CC)(=O)=O)#N>>[C:1]([C:3]1[CH:4]=[C:5]([NH:14][C:15](=[O:27])[O:16][CH2:17][CH2:18][C:19]2[C:24]([CH3:29])=[CH:23][C:22]([Br:25])=[CH:21][C:20]=2[CH3:26])[CH:6]=[CH:7][C:8]=1[S:9]([CH2:12][CH3:13])(=[O:10])=[O:11])#[N:2]

참가 물질

4

반응물 3

HCID 578427022-(4-Bromo-2,6-dimethylphenyl)ethanolHCID 578428634-Bromo-2-methylphenethyl 3-cyano-4-(ethylsulfonyl)phenylcarbamateHCID 68818495HCID 68818495, 화합물

생성물 1

HCID 57842545HCID 57842545, 화합물수율 59%

실험 절차

Using a procedure analogous to that used to prepare 31A, 32B (400 mg, 1.75 mmol) was reacted with 25A (579 mg, 1.75 mmol) to give 32C (480 mg, 59%) as a white solid. MS (ESI) m/z 465.1/467.1 (M+H)+.

출처 및 근거

ORD 기록
ord-d60a2931795b4741a689d1c773fe0b0b
출처 데이터셋
uspto-grants-2009_09
특허 번호
US07592331B2

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