反应详情

To a solution of ethyl{(4-aminobenzyl)[4-(trifluoromethyl)benzyl]amino}(oxo)acetate (38 mg, 0.10 mmol) and 1,2-dodecylene oxide (22 mg, 0.12 mmol) in 1.0 mL CH3CN were added at once magnesium perchlorate (27 mg, 0.12 mmol) under inert atmosphere. The reaction mixture was stirred 24 at rt. 2 mL of H2O were added and the resulting mixture was extracted with EtOAc (2×5 mL), dried over MgSO4, filtered and the solvents were evaporated under vacuum to give a slightly yellow oil (61 mg).

1. extractionthe resulting mixture was extracted with EtOAc (2×5 mL)
2. dry with materialdried over MgSO4
3. filtrationfiltered
4. customthe solvents were evaporated under vacuum