反应详情

A mixture of methyl-3-bromo-4-methylbenzoate (40 g, 0.17 mol), NBS (34 g, 0.19 mol) and benzoylperoxide (4.0 g) in CCl4 (500 mL) was refluxed for 6 h. The reaction mixture was cooled and filtered off the solid. The filtrate was concentrated under vacuum to give 2-bromo-4-methoxycarbonylbenzyl bromide (50 g, 93%) as a solid.

1. temperaturewas refluxed for 6 h
2. temperatureThe reaction mixture was cooled
3. filtrationfiltered off the solid
4. concentrationThe filtrate was concentrated under vacuum