HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → Methyl 3-bromo-4-(bromomethyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | Methyl 3-bromo-4-methylbenzoate | HCID 7015747 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | Methyl 3-bromo-4-(bromomethyl)benzoate | HCID 10804694 | 95.5% |
Reaction Steps
A mixture of methyl-3-bromo-4-methylbenzoate (40 g, 0.17 mol), NBS (34 g, 0.19 mol) and benzoylperoxide (4.0 g) in CCl4 (500 mL) was refluxed for 6 h. The reaction mixture was cooled and filtered off the solid. The filtrate was concentrated under vacuum to give 2-bromo-4-methoxycarbonylbenzyl bromide (50 g, 93%) as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592477B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-a9d8b506e1e94502b94a85888fae1621 |
| Source note | uspto-grants-2009_09 |