HCID 67188291, compound → HCID 67188292, compound

HRID 735868Notes

Reaction equation

HRID 735868 reaction equation
Cl.[NH2:2][CH2:3][C:4]1[CH:24]=[CH:23][C:7]([C:8]([NH:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[O:9])=[CH:6][CH:5]=1>CCOC(C)=O>[NH2:2][CH2:3][C:4]1[CH:5]=[CH:6][C:7]([C:8]([NH:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[O:9])=[CH:23][CH:24]=1

Participants

3

Reactant 1

HCID 67188291HCID 67188291, compound

Product 1

HCID 67188292HCID 67188292, compoundYield 90.5%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A suspension of 4-(aminomethyl)-N-dodecylbenzamide hydrochloride (1.97 g) in AcOEt (100 mL) was washed with a saturated aqueous solution of NaHCO3 (50 mL). The organic layer was dried over MgSO4 and evaporated to give the title compound as a white solid (1.6 g).

Workup

  1. washwas washed with a saturated aqueous solution of NaHCO3 (50 mL)
  2. dry with materialThe organic layer was dried over MgSO4
  3. customevaporated

Sources & evidence

ORD record
ord-6b11fd6115744b089e1f37f458ddabe3
Source dataset
uspto-grants-2009_09
Patent number
US07592477B2

Reaction notes

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