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HRID735903

反应详情

EQUATION

反应方程式

HRID 735903 的结构方程式

REACTANTS

反应物

2
结构：C[C@@H](N)c1ccc(C(F)(F)F)cc1
HCID821259

(R)-1-[4-(Trifluoromethyl)phenyl]ethylamine

C9H10F3N

结构：CCCCCCCCCCCc1noc(-c2ccc(C=O)cc2)n1
HCID86598531

未命名化合物

PRODUCTS

生成物

1
结构：CCCCCCCCCCCc1noc(-c2ccc(CN[C@H](C)c3ccc(C(F)(F)F)cc3)cc2)n1
HCID67187997

未命名化合物

收率 71%

PROCEDURE

实验过程

The same procedure as employed in the preparation of Example 226 (step a) but using 4-(3-undecyl-1,2,4-oxadiazol-5-yl)benzaldehyde and (1R)-1-[4-(trifluoromethyl)phenyl]ethylamine gave the title compound as a colorless oil (71%). M+(LC/MS(ESI)): 502.4. HPLC (Condition A), Rt: 5.04 min (HPLC purity: 99.6%).

WORKUP

后处理

  1. customThe same procedure as employed in the preparation of Example 226 (step a) but