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HRID735905

反应详情

EQUATION

反应方程式

HRID 735905 的结构方程式

REACTANTS

反应物

2
结构：C[C@H](N)c1ccc(C(F)(F)F)cc1
HCID2779052

(1S)-1-[4-(Trifluoromethyl)phenyl]ethan-1-amine

C9H10F3N

结构：O=Cc1ccc(C(=O)OCc2ccccc2)cc1
HCID11528845

未命名化合物

PRODUCTS

生成物

1
结构：C[C@H](NCc1ccc(C(=O)OCc2ccccc2)cc1)c1ccc(C(F)(F)F)cc1
HCID67187817

未命名化合物

收率 83%

PROCEDURE

实验过程

The same procedure as employed in the preparation of Example 226 (step a) but using benzyl 4-formylbenzoate and (1S)-1-[4-(trifluoromethyl)phenyl]ethylamine gave the title compound as a pale yellow oil (83%). M+(LC/MS(ESI)): 414.3. HPLC (Condition A), Rt: 3.77 min (HPLC purity: 99.1%).

WORKUP

后处理

  1. customThe same procedure as employed in the preparation of Example 226 (step a) but