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HRID735949

反应详情

EQUATION

反应方程式

HRID 735949 的结构方程式

REACTANTS

反应物

2
结构：NCc1ccc(C(F)(F)F)cc1
HCID76804

4-(Trifluoromethyl)benzylamine

C8H8F3N

结构：CCCCCCCCCCC#Cc1cccc(C=O)c1
HCID18372994

未命名化合物

PRODUCTS

生成物

1
结构：CCCCCCCCCCC#Cc1cccc(CNCc2ccc(C(F)(F)F)cc2)c1
HCID67187424

未命名化合物

收率 37%

PROCEDURE

实验过程

The same procedure as employed in the preparation of Example 226 (step a) but using 3-dodec-1-ynylbenzaldehyde and 4-(trifluoromethyl)benzylamine gave the title compound (37%). M+(LC/MS(ESI)): 430.5. HPLC (Condition A), Rt: 4.82 min (HPLC purity 94.7%).

WORKUP

后处理

  1. customThe same procedure as employed in the preparation of Example 226 (step a) but