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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 735949Generated: October 29, 2026

4-(Trifluoromethyl)benzylamine → N-(3-dodec-1-ynylbenzyl)-N-[4-(trifluoromethyl)benzyl]amine

https://huagongshe.com/reaction/735949

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)benzylamineHCID 76804—
Reactant3-(1-Dodecynyl)benzaldehydeHCID 18372994—
ProductN-(3-dodec-1-ynylbenzyl)-N-[4-(trifluoromethyl)benzyl]amineHCID 6718742437%

Reaction Steps

The same procedure as employed in the preparation of Example 226 (step a) but using 3-dodec-1-ynylbenzaldehyde and 4-(trifluoromethyl)benzylamine gave the title compound (37%). M+(LC/MS(ESI)): 430.5. HPLC (Condition A), Rt: 4.82 min (HPLC purity 94.7%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07592477B2
Source datasetuspto-grants-2009_09
ORD IDord-79cdd4f757b34e7bbaaa846a40963752
Source noteuspto-grants-2009_09