HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-((Trifluoromethyl)sulfonyl)benzylamine hydrochloride → N-{4-[(trifluoromethyl)sulfonyl]benzyl}-N-[3-(3-undecyl-1,2,4-oxadiazol-5-yl)benzyl]amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-((Trifluoromethyl)sulfonyl)benzylamine hydrochloride | HCID 67188273 | — |
| Reactant | 3-(3-Undecyl-1,2,4-oxadiazol-5-yl)benzaldehyde | HCID 86598538 | — |
| Product | N-{4-[(trifluoromethyl)sulfonyl]benzyl}-N-[3-(3-undecyl-1,2,4-oxadiazol-5-yl)benzyl]amine | HCID 67187372 | — |
Reaction Steps
The same procedure as employed in the preparation of Example 357 (step a) but using 3-(3-undecyl-1,2,4-oxadiazol-5-yl)benzaldehyde and 4-[(trifluoromethyl)sulfonyl]benzylamine hydrochloride gave the title compound as an oil. M+(LC/MS(ESI)): 552.5. HPLC (Condition A), Rt: 4.85 min (HPLC purity: 62.0%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592477B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-54e7d93f6fe8481fb72ae4490b396842 |
| Source note | uspto-grants-2009_09 |