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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 735996Generated: October 25, 2026

2-(Trifluoromethyl)benzylamine → N-(4-dodec-1-ynylbenzyl)-N-[2-(trifluoromethyl)benzyl]amine

https://huagongshe.com/reaction/735996

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactant4-Dodec-1-ynylbenzaldehydeHCID 86598536—
ProductN-(4-dodec-1-ynylbenzyl)-N-[2-(trifluoromethyl)benzyl]amineHCID 67185985—

Reaction Steps

The same procedure as employed in the preparation of Example 394 (step b) but using 4-dodec-1-ynylbenzaldehyde and 2-(trifluoromethyl)benzylamine gave the title compound as an oil. M+(LC/MS(ESI)): 430.4. HPLC (Condition A), Rt: 5.05 min (HPLC purity: 96.9%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07592477B2
Source datasetuspto-grants-2009_09
ORD IDord-36bd7ebffb064a16891cdcb79426cbfa
Source noteuspto-grants-2009_09