Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Bromoanisole | HCID 16971 | — |
| Reactant | Phenylboronic Acid | HCID 66827 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | 3-Methoxybiphenyl | HCID 257971 | — |
Reaction Steps
190 mg 3-bromoanisole, 183 mg phenyl boronic acid and 275 mg potassium carbonate are mixed in 2 ml xylene. To this is added 27 mg of the catalyst from example 5a (corresponds to 0.5 mol % palladium). The reaction mixture is stirred and heated, under an atmosphere of nitrogen, to a temperature of 130° C. for a period of 2 hours. A GC analysis showed that all starting material is consumed and 3-methoxy biphenyl is formed selectively (100% conversion).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07594962B2 |
|---|
| Source dataset | uspto-grants-2009_09 |
|---|
| ORD ID | ord-8f78df08e1de48d4a07cb8ff47581ed9 |
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| Source note | uspto-grants-2009_09 |
|---|
