HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Morpholin-4-yl-5-nitro-benzoyl chloride → [4-(2-Fluoro-4-methyl-phenyl)-piperazin-1-yl]-(2-morpholin-4-yl-5-nitro-phenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Morpholin-4-yl-5-nitro-benzoyl chloride | HCID 17274153 | — |
| Reactant | 1-(2-Fluoro-4-methylphenyl)piperazine | HCID 21363777 | — |
| Product | [4-(2-Fluoro-4-methyl-phenyl)-piperazin-1-yl]-(2-morpholin-4-yl-5-nitro-phenyl)-methanone | HCID 59793739 | 70% |
Reaction Steps
Title compound was prepared according to procedure described in example 46 from 1-(2-Fluoro-4-methyl-phenyl)-piperazine and 2-morpholin-4-yl-5-nitro-benzoyl chloride (70% yield, yellow oil, MS (m/e): 429.2 (M+H+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07595314B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-c50d5765684540b78f5a814efe886169 |
| Source note | uspto-grants-2009_09 |