反应详情

2-(4-{1-Ethyl-1-[4-(3-ethyl-3-hydroxy-pent-1-ynyl)-3-methyl-phenyl]-propyl}-2-methyl-benzoylamino)-2-methyl-propionic acid methyl ester (3.97 mg, 0.785 mmol) and lithium hydroxide (56 mg, 2.36 mmol) are reacted and purified analogous to Example 1I to give the title compound (384 mg, 99%).

1. custompurified analogous to Example 1I