Ethyl Bromide → HCID 86600819, compound

HRID 736568Notes

Reaction equation

HRID 736568 reaction equation
[CH2:1]([Br:3])[CH3:2].[CH3:4][N:5]([CH3:33])[CH2:6][CH2:7][CH2:8][O:9][N:10]=[C:11]1[CH2:16][C:15]([CH2:18][CH3:19])([CH3:17])[N:14]([O:20][CH:21]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH3:22])[C:13]([CH2:30][CH3:31])([CH3:29])[CH:12]1[CH3:32]>C(#N)C>[Br-:3].[CH2:30]([C:13]1([CH3:29])[CH:12]([CH3:32])[C:11](=[N:10][O:9][CH2:8][CH2:7][CH2:6][N+:5]([CH2:1][CH3:2])([CH3:4])[CH3:33])[CH2:16][C:15]([CH2:18][CH3:19])([CH3:17])[N:14]1[O:20][CH:21]([C:23]1[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=1)[CH3:22])[CH3:31]

Participants

4

Reactant 2

HCID 6332Ethyl BromideHCID 86600818HCID 86600818, compound

Product 1

HCID 86600819HCID 86600819, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Ethylbromide (7.5 ml) is added to a solution of 2,6-diethyl-2,3,6-trimethyl-1-(1-phenyl-ethoxy)-piperidine-4-one-O-(3-dimethylamino-propyl)-oxime (10.2 g, 0.0244 mol) in acetonitrile (12 ml). The solution is stirred 24 h at room temperature and is then evaporated. The residue is dissolved in dichloromethane, dried over MgSO4 and evaporated to afford 11.5 g of the title compound as a white powder.

Workup

  1. customis then evaporated
  2. dissolutionThe residue is dissolved in dichloromethane
  3. dry with materialdried over MgSO4
  4. customevaporated

Sources & evidence

ORD record
ord-24daf11777014453b71478ae80af13e9
Source dataset
uspto-grants-2009_09
Patent number
US07595359B2

Reaction notes

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