Hydrochloric Acid → HCID 68817491, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 4-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylamino]-tetrahydro-furan-3-carboxylic acid methyl ester (0.9 g, 1.97 mmol) in 1,4-dioxane (4 mL) was added concentrated HCl (4 mL). The reaction was heated to 60° C. for 19 h. The solvent was removed in vacuo to provide 4-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylamino]-tetrahydro-furan-3-carboxylic acid as a crude solid (0.6 g, 69%). MS: 443 (M+H)+

Provenance & Evidence