反应详情

(3R,4R)-4-(4-(Benzyloxy)phenylsulfonamido)-N-tert-butoxy-3-methyl-tetrahydro-2H-pyran-3-carboxamide was dissolved in ethyl acetate (25 mL), 10% palladium on carbon (90 mg) was added, and the resulting reaction mixture was stirred under a hydrogen balloon overnight. The reaction mixture was then filtered and concentrated to provide (3R,4R)-N-tert-butoxy-4-(4-hydroxyphenylsulfonamido)-3-methyl-tetrahydro-2H-pyran-3-carboxamide as a white solid that was used in the next step without purification. MS: (M+Na)+=409.0; (M−H)−=385.2.

1. customthe resulting reaction mixture
2. filtrationThe reaction mixture was then filtered
3. concentrationconcentrated