HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 736947Generated: October 26, 2026
Trifluoroacetic acid → HCID 68591763, compound
https://huagongshe.com/reaction/736947
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 1,1-Dimethylethyl 4-[4-(trifluoroacetyl)phenyl]-1-piperazinecarboxylate | HCID 69249639 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 68591763 | HCID 68591763 | — |
Reaction Steps
2.0 mL TFA were added to a solution of 267 mg (0.75 mmol) tert. butyl 4-[4-(2,2,2-trifluoro-acetyl)-phenyl]-piperazin-1-carboxylate in 30 mL DCM cooled to 0° C. and the reaction mixture was stirred for 24 h, while warming up to RT. It was evaporated down i.vac.; the crude product was further reacted without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07595312B2 |
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| Source dataset | uspto-grants-2009_09 |
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| ORD ID | ord-d7e32d0443be4737918c03244e9d64ed |
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| Source note | uspto-grants-2009_09 |
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