Bromine → 5-acetyl-2-Furancarboxylic acid methyl ester

HRID 737187Notes

Reaction equation

HRID 737187 reaction equation
BrBr.[CH3:3][O:4][C:5]([C:7]1[O:8][C:9]([C:12](=[O:15])[CH2:13]Br)=[CH:10][CH:11]=1)=[O:6]>CC(O)=O>[CH3:3][O:4][C:5]([C:7]1[O:8][C:9]([C:12](=[O:15])[CH3:13])=[CH:10][CH:11]=1)=[O:6]

Participants

4

Reactant 2

HCID 24408BromineHCID 14945157Methyl 5-(2-bromoacetyl)furan-2-carboxylate

Product 1

HCID 122812255-acetyl-2-Furancarboxylic acid methyl ester

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Bromination of 5-acetyl-furan-2-carboxylic acid methyl ester (0.27 g, 1.61 mmol) with Br2 (0.082 mL) in AcOH (6 mL) at room temperature gave 5-(2-bromo-acetyl)-furan-2-carboxylic acid methyl ester; MS: 246.1 (M+H+).

Sources & evidence

ORD record
ord-893a7dce008b4f8b82f1fe47f51916d8
Source dataset
uspto-grants-2009_09
Patent number
US07595398B2

Reaction notes

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